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  • Anastasius
    Full Member
    • Mar 2015
    • 1842

    Originally posted by teamsaint View Post
    At what point do you think such trials should happen, S-A?

    Everybody in vulnerable groups has been offered at least one vaccine. Incidence is low. We are out of the main season for respiratory disease. There is evidence of herd immunity. People attending are either vaccinated or tested.

    ( Though as we know,vaccinated people can still spread the virus......)
    There is evidence of herd immunity.

    Who says that, TS ? Source please.

    And ...

    Though as we know,vaccinated people can still spread the virus. And compared to someone not vaccinated and with a significantly higher viral load is what ? About 1% the risk to others?
    Fewer Smart things. More smart people.

    Comment

    • Anastasius
      Full Member
      • Mar 2015
      • 1842

      Originally posted by teamsaint View Post
      Because they have covid antibodies.

      The question in fact should be “ why would they want the vaccine when they have antibodies, and there are known serious side effects from the vaccine, especially for younger people”.
      You are starting to sound more and more like the sort of headlines that the Daily Mail screams out, TS. You make these sweeping statements without any attempt at quantifying them.
      Fewer Smart things. More smart people.

      Comment

      • Anastasius
        Full Member
        • Mar 2015
        • 1842

        Originally posted by teamsaint View Post
        So the figures you show are the risk profile for those without prior immunity ? Evidence about how these particular vaccines work for those with prior immunity must be very sketchy at best, at present?
        Straws. Grasping.
        Fewer Smart things. More smart people.

        Comment

        • teamsaint
          Full Member
          • Nov 2010
          • 25200

          Originally posted by Anastasius View Post
          There is evidence of herd immunity.

          Who says that, TS ? Source please.

          And ...

          Though as we know,vaccinated people can still spread the virus. And compared to someone not vaccinated and with a significantly higher viral load is what ? About 1% the risk to others?
          Lots of reputable sources are suggesting that herd immunity is probably kicking in.

          I wasn’t comparing the risk of transmission between unvaccinated and vaccinated. Just pointing out that there is a measurable risk that vaccinated people can transmit the disease, something that seems to be less widely understood than you might think. This is important.
          I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.

          I am not a number, I am a free man.

          Comment

          • teamsaint
            Full Member
            • Nov 2010
            • 25200

            Originally posted by Anastasius View Post
            Straws. Grasping.
            No, trying to read the figures that LHC posted. And putting the evidence in context, which is important.
            I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.

            I am not a number, I am a free man.

            Comment

            • teamsaint
              Full Member
              • Nov 2010
              • 25200

              Originally posted by Anastasius View Post
              You are starting to sound more and more like the sort of headlines that the Daily Mail screams out, TS. You make these sweeping statements without any attempt at quantifying them.
              You’ll see that upthread I quoted the ONS figures, and asked a question. How much quantifying do you want beyond ONS figures?

              Which is a long way from your take on it, which hasn’t added anything to the discussion, in fact.
              I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.

              I am not a number, I am a free man.

              Comment

              • oddoneout
                Full Member
                • Nov 2015
                • 9150

                I found this article interesting as it touches on a question that arose in my mind after hearing about the antibody levels in those who are neither vaccinated nor known to have contracted the disease. I remember at school there was a preliminary stage to the BCG vaccine to test for natural/pre-existing immunity, and I was told that my grandmother had natural immunity.
                It seemed a truth universally acknowledged that the human population had no pre-existing immunity to SARS-CoV-2, but is that actually the case? Peter Doshi explores the emerging research on immunological responses Even in local areas that have experienced some of the greatest rises in excess deaths during the covid-19 pandemic, serological surveys since the peak indicate that at most only around a fifth of people have antibodies to SARS-CoV-2: 23% in New York, 18% in London, 11% in Madrid.123 Among the general population the numbers are substantially lower, with many national surveys reporting in single digits. With public health responses around the world predicated on the assumption that the virus entered the human population with no pre-existing immunity before the pandemic,4 serosurvey data are leading many to conclude that the virus has, as Mike Ryan, WHO’s head of emergencies, put it, “a long way to burn.” Yet a stream of studies that have documented SARS-CoV-2 reactive T cells in people without exposure to the virus are raising questions about just how new the pandemic virus really is, with many implications. At least six studies have reported T cell reactivity against SARS-CoV-2 in 20% to 50% of people with no known exposure to the virus.5678910 In a study of donor blood specimens obtained in the US between 2015 and 2018, 50% displayed various forms of T cell reactivity to SARS-CoV-2.511 A similar study that used specimens from the Netherlands reported T cell reactivity in two of 10 people who had not been exposed to the virus.7 In Germany reactive T cells were detected in a third of SARS-CoV-2 seronegative healthy donors (23 of 68). In Singapore a team analysed specimens taken from people with no contact or personal …

                Tragic as the consequences of the pandemic have been and continue to be, it has accelerated research in areas which will help with the treatment of disease, whether pandemic or not, in future.

                Comment

                • Anastasius
                  Full Member
                  • Mar 2015
                  • 1842

                  Originally posted by teamsaint View Post
                  Because they have covid antibodies.

                  The question in fact should be “ why would they want the vaccine when they have antibodies, and there are known serious side effects from the vaccine, especially for younger people”.
                  .....
                  Can you perhaps confirm, given your views on the Covid vaccination, that you will be declining the opportunity when it arises ?
                  Fewer Smart things. More smart people.

                  Comment

                  • Anastasius
                    Full Member
                    • Mar 2015
                    • 1842

                    Originally posted by teamsaint View Post
                    You’ll see that upthread I quoted the ONS figures, and asked a question. How much quantifying do you want beyond ONS figures?

                    Which is a long way from your take on it, which hasn’t added anything to the discussion, in fact.
                    Others have done it already and far more eloquently than I can. Just that you refuse to accept it.
                    Fewer Smart things. More smart people.

                    Comment

                    • teamsaint
                      Full Member
                      • Nov 2010
                      • 25200

                      Originally posted by Anastasius View Post
                      You are starting to sound more and more like the sort of headlines that the Daily Mail screams out, TS. You make these sweeping statements without any attempt at quantifying them.

                      Can you perhaps confirm, given your views on the Covid vaccination, that you will be declining the opportunity when it arises ?
                      You have no idea what my views are on covid vaccination, I’d suggest, other than you will have gathered that I don’t think we should vaccinate people in cases where it is not necessary. Which is self evident of course.
                      My decisions are my own business, nobody elses.
                      Last edited by teamsaint; 01-05-21, 07:43.
                      I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.

                      I am not a number, I am a free man.

                      Comment

                      • teamsaint
                        Full Member
                        • Nov 2010
                        • 25200

                        Originally posted by Anastasius View Post
                        Others have done it already and far more eloquently than I can. Just that you refuse to accept it.
                        No, I asked a question to clarify an important point.
                        You are trolling, not engaging with the subject.
                        I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.

                        I am not a number, I am a free man.

                        Comment

                        • Bryn
                          Banned
                          • Mar 2007
                          • 24688

                          Originally posted by teamsaint View Post
                          Lots of reputable sources are suggesting that herd immunity is probably kicking in.

                          I wasn’t comparing the risk of transmission between unvaccinated and vaccinated. Just pointing out that there is a measurable risk that vaccinated people can transmit the disease, something that seems to be less widely understood than you might think. This is important.
                          Certainly, herd immunity is 'kicking in'. That's what mass immunisation accelerates. There are two principal routes to herd immunity. previous infection and immunisation. Far better to gain it though the latter than the former. What I would question is whether you understand the relative level of contribution to spreading to which virus sheding by those immunised might make?

                          Comment

                          • teamsaint
                            Full Member
                            • Nov 2010
                            • 25200

                            Originally posted by Bryn View Post
                            Certainly, herd immunity is 'kicking in'. That's what mass immunisation accelerates. There are two principal routes to herd immunity. previous infection and immunisation. Far better to gain it though the latter than the former. What I would question is whether you understand the relative level of contribution to spreading to which virus sheding by those immunised might make?
                            Yes, I think I probably do understand that in in its correct context, ie that transmission happens less often, and to less effect.
                            It is an important point. But it is also important, both medically and socially, that we understand that vaccination does not mean that people cannot transmit the virus. But unfortunately that understanding doesn’t seem to be widely understood, and ( wilfully) isn’t informing public policy.
                            I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.

                            I am not a number, I am a free man.

                            Comment

                            • LHC
                              Full Member
                              • Jan 2011
                              • 1556

                              Originally posted by teamsaint View Post
                              So the figures you show are the risk profile for those without prior immunity ? Evidence about how these particular vaccines work for those with prior immunity must be very sketchy at best, at present?
                              its worth remembering as well that, although young people are at much less risk of hospitalisation and death from Covid, there is also the risk of additional complications from a Covid infection such as Long Covid, which are still not well understood. These longer terms effects will only become known and better understood over time, so the risk profile for younger people could well change. There is also some evidence that the new variants are proving to be more dangerous for younger people than the first waves of the disease last year (in that more young people appear now to be having serious consequences from an infection).

                              It is not clear to me at all that there is any basis for suggesting that there may be no need to vaccinate people in the 18 - 29 age group.
                              "I do not approve of anything that tampers with natural ignorance. Ignorance is like a delicate exotic fruit; touch it and the bloom is gone. The whole theory of modern education is radically unsound. Fortunately in England, at any rate, education produces no effect whatsoever. If it did, it would prove a serious danger to the upper classes, and probably lead to acts of violence in Grosvenor Square."
                              Lady Bracknell The importance of Being Earnest

                              Comment

                              • teamsaint
                                Full Member
                                • Nov 2010
                                • 25200

                                Originally posted by LHC View Post
                                its worth remembering as well that, although young people are at much less risk of hospitalisation and death from Covid, there is also the risk of additional complications from a Covid infection such as Long Covid, which are still not well understood. These longer terms effects will only become known and better understood over time, so the risk profile for younger people could well change. There is also some evidence that the new variants are proving to be more dangerous for younger people than the first waves of the disease last year (in that more young people appear now to be having serious consequences from an infection).

                                It is not clear to me at all that there is any basis for suggesting that there may be no need to vaccinate people in the 18 - 29 age group.
                                Yes, post viral complications are important to bring into the discussion. There are , at this stage lots of unknowns,( including long term effects of the vaccines) so it is a question of playing the percentages .
                                I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.

                                I am not a number, I am a free man.

                                Comment

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